Microfluidic Chem-Bio Sensors

Center research developed low cost fabrication technologies capable of producing high resolution micro-nanoscale surface patterns and structures useful for high sensitivity optical sensing of extremely low (picco to atto molar) concentrations and picco liter volumes.  A variety of photonic devices can be made that control light in the sub-wavelength regime.  These devices incorporated into microfluidic channels and well-plates can find application in:

  • High throughput drug screening
  • Cell-based assays
  • Detecting protein-DNA interactions

Using the Nanoreplica Molding process, high precision patterned surfaces can be economically fabricated in high volume using a variety of materials including:

  • High refractive index dielectric materials
  • Electro-optic materials
  • Conducting electrodes
  • Ionized gas
  • Biocompatible polymers

This low cost process can produce very high precision micro-nanoscale patterns and structures by using a rigid silicon master and a photocurable liquid polymer.

For more information, please download the full description of this research.